None of the popular live-action Nick shows from the 2000s to early 2010s had a graduation episode.
I just noticed one subtle pattern with every popular Nick show from the 2000s to early 2010s. None of them ended with an episode where the main cast graduated. Why did I mention this? Because graduation from high school is essentially the conclusion of your teenage years.
Here's the shows I'm talking about and the main plot of their ending. Disclaimer: I didn't watch all of their finales.
- Drake & Josh - Drake's hit music + Helen's wedding
- Zoey 101 - prom
- iCarly - Carly moves to Italy
- Victorious - no formal ending
- Big Time Rush - new song ending
- Sam & Cat - no formal ending
Not sure which live actions afterward 2014 had a graduation.