Arriving late at night

Hi guys - first time visiting Venice this year, 40F solo this April. My flight lands around 11pm - it seems I can get a bus from the Airport to the Piazalle Roma, then get the "N" water taxi, then a few mins walk to my hotel - will be reaching the hotel after midnight. My main question is, will that be safe? I don't see another alternative, but my hotel is a very short distance from where I would get off the water taxi. Thank you!