Characters that are supposed to be funny but just make you uncomfortable
Originally my answer was going to be Mr. Boss from Smiling Friends. I get that his creepiness is part of the joke, but he's just too weird most of the time. Especially in his first scene. But that Jared Fogle joke from the most recent episode was actually pretty funny so he gets a pass for now.
So my actual answer is going to be Quetzalcoatl from Miss Kobayashis Dragon Maid. Like, listen show, I dont care how much you run this stupid joke into the ground, a grown woman doting on a child named "Shota" and putting her massive boobs in his face is not funny. At first I thought she might have just been teasing him, which still would have been weird, but apparently a spin-off comic confirms that she marries him when he becomes an adult.