Estradiol Vaginal Cream -> Depressed? Weight gain?

Hello, 56 yo here. I started using 2 grams nightly on August 17. Last night, depression hit me like a truck out of nowhere. I started this medicine for vaginal atrophy which was really the only reason. Otherwise my symptoms have been mild and I read on the internet that this medicine can cause depression. I was fine all week and then last night on my way home from work I started feeling sad. It had been a long week (first week back - I’m a teacher) and I wonder if being busy kept the depression at bay. And after this long stressful week I cooked for 45 minutes and finally sat down to eat at about 8 pm a delicious favorite meal. Well a fly landed on my food. I was upset, but I fanned it away and figure I would eat the food on the other side of my plate. Then it landed on my plate again in the other part and lost it . I threw my food away and cried the rest of the night, fell asleep and this morning still felt bad. And even with skipping dinner, i was up another lb. That’s three I’ve gained since last week.

Are these side effects normal? And are they temporary? I would rather have my vagina atrophy than cry any time I am not busy. I also can’t afford to gain any more weight, I’ve actually been eating healthy and exercising a ton so it’s super discouraging to see the scale go up after this hard work, just as it is to throw away a dinner that took so much time and effort.

I am already on Wellbutrin and Buspar for depression and anxiety and they’ve worked great for several years. The doctor who prescribed Estradiol wants me to use 2-4 grams every day for two weeks and then use that amount twice a week thereafter. I’m using 2, the minimum. Will things even out? Will they improve when I go down to twice a week? Or do just stop completely and hope to get back to my normal weight and emotional state?

Feeling very fat and hopeless right now.